Section A: Presents a systematic search and narrative review of research into the association between social relationships and depression in men. Social relationships are defined with reference to three key areas of research, and some proposed causal links with depression are outlined. A review of relevant studies identifies some patterns in findings, but also substantial limitations of the extant literature. Implications for clinical practice are considered, including a need to consider the quality of men’s relationships during the assessment of depression and as a target of therapeutic interventions. Recommendations for future research include the need for well-designed longitudinal studies, and qualitative research exploring how men draw on relationships to maintain their emotional wellbeing. Section B: Presents a study in which grounded theory methodology was used to generate a model of contemporary men’s talking groups. The model first describes the experiences leading men to seek out and attend a group. Processes operating in the group are defined, with an emphasis on creating a safe space for men to self-disclose, interrogate the concept of manhood, and create authentic, deep relationships with one another. The perceived benefits of these processes beyond the group are described. The model is linked to theories of group psychotherapy, social identity and social relationships. Implications for practice and research are considered.