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Title: The epidemiology of bronchial carcinoma : a description and follow-up of all the cases diagnosed in the area of the Blackburn H.M.C. during 1955, together with comparative figures from the literature and a review of present theories of causation
Author: Stalker, Randal
Awarding Body: University of Edinburgh
Current Institution: University of Edinburgh
Date of Award: 1957
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Abstract:
According to Hueper (1942) cancer of the lung, under the name of "mala metallorum", was reported by Paracelsus in 1531 as occurring among miners in Schneeberg. The disease was recognised by Baillie in 1796 (Morbid Anatomy). Laennec described cancer of the lung in 1805 in the Dictionnaire des Science iiedicales, and again in 1819, in his famous treatise De L'Auscultation Mediate. In 1837 Stokes in his Treatise on the Diagnosis and Treatment of Diseases of the Chest directed attention to the clinical manifestations, and in 1838 Carswell in his Pathological Anatomy emphasized the primary nature of the tumour. During the latter half of the 19th Century many individual cases were reported. In 1897 West reported 155 cases from St. Bartholomew's Hospital and the Transactions of the Pathological Society. In 1912 Adler in his monograph Primary Malignant Growths of the Lungs and Bronchi described 374 collected cases of primary lung cancer. Bronchoscopic biopsy came into use between 1910 and 1915. Packard in 1917 described the clinical manifestations in terms pf physical signs, X -Ray shadows and bronchoscopie findings. Rosenblatt and Lisa (1956) describe necropsy studies since 1852. As far back as the period 1898 -1902 Junghannt found primary lung cancer to account for 11.62% of all cancers seen at necropsy in Dresden. Surgical resection for lung cancer had been attempted in 1916 by Morriston Davies, and in 1917 by Sauerbruch, but the first successful pneumonectomy for this disease was performed by Graham in America in 1933. In the same year two stage pneumonectomy was carried out by Price Thomas and Tudor Edwards. It was not until 1939 that the technique of dissection resection as we know it today was evolved, (Wooler 1957). Statistical trends will be discussed later, but in 1925 in England and Wales less than 3,000 deaths were recorded for respiratory cancer (larynx, trachea, lung and pleura, unspecified as to whether primary or secondary, male and female). By 1933 the figure was nearing 4,000 and it was approaching the 10,000 mark in 1946 7 after the end of the war. Surgical resection for lung cancer had been attempted in 1916 by Morriston Davies, and in 1917 by Sauerbruch, but the first successful pneumonectomy for this disease was performed by Graham in America in 1933. In the same year two stage pneumonectomy was carried out by Price Thomas and Tudor Edwards. It was not until 1939 that the technique of dissection resection as we know it today was evolved, (Wooler 1957). Statistical trends will be discussed later, but in 1925 in England and Wales less than 3,000 deaths were recorded for respiratory cancer (larynx, trachea, lung and pleura, unspecified as to whether primary or secondary, male and female). By 1933 the figure was nearing 4,000 and it was approaching the 10,000 mark in 1946-7 after the end of the war. Epidemiological information must be made available for the scientist, surgeon, statistician or pathologist. Some of this information such as smoking habits, occupation, place of residence, previous medical history and pathology is best studied among groups of proved cases. But in order to study age /sex incidence, the frequency of the various histological types, diagnotic criteria and the value of death certification, absolute figures of operability, survival period and the average condition of the patients on first diagnosis it is necessary to include all the cases occurring in one area.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (M.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.798773  DOI: Not available
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