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Title: Small bowel motility in ulcerative colitics undergoing ileal pouch-anal anastomosis
Author: McCourtney, James S.
Awarding Body: University of Glasgow
Current Institution: University of Glasgow
Date of Award: 1998
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Although much clinical research has been carried out in the last 14 years to examine the postoperative function of patients undergoing ileal pouch-anal anastomosis (IPAA), little is known about the small bowel which is used to create the reservoir in this procedure. This thesis has therefore examined the preoperative small bowel motility characteristics of patients with ulcerative colitis (UC) undergoing EPAA using in vivo and in vitro techniques. The in vitro studies were compared against control subjects of whom most were undergoing elective right hemicolectomy for non-obstructing neoplasms. During part of the research project access to ileal tissue from patients with idiopathic slow transit constipation (ISTC) undergoing subtotal colectomy and ileorectal anastomosis (SC+IRA) enabled a study of this interesting subgroup of patients to be made. A review of the IPAA operation performed at Glasgow Royal Infirmary between 1988 and 1995 i.e. totally stapled restorative proctocolectomy (TSRP), was also carried out.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (M.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available