Use this URL to cite or link to this record in EThOS: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.797054
Title: Biological equivalence between different radiotherapy schedules studied using the linear quadratic model
Author: Deehan, Charles
Awarding Body: University of Glasgow
Current Institution: University of Glasgow
Date of Award: 1995
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Abstract:
The aim of this work was to investigate biological equivalence between different radiotherapy treatment schedules. The first three chapters form an introduction to radiobiological aspects of radiotherapy, these discuss radiation effects on cells and tissues, radiobiological models in radiotherapy and biological equivalence. In chapters 4, 5 and 6 conditions for general equivalence are derived for fractionated, continuous and combined treatments, based on biological effect calculations performed at specific points in a dose distribution. Chapters 7 and 8 introduce the subject of iso-effect surfaces and this concept is applied to both continuous and fractionated treatments. Finally results of this thesis are compared with clinical reports in chapter 9. The Linear Quadratic (LQ) iso-effect model is used in the derivation of general equivalence relationships and in iso-effect surface calculations.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.797054  DOI: Not available
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