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Title: Studies of the relationship between mRNA stability and gene function in Saccharomyces cerevisiae
Author: Moore, Joyce
Awarding Body: University of Glasgow
Current Institution: University of Glasgow
Date of Award: 1991
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Twelve S. cerevisiae cDNAs, characterised by Santiago (1986) on the basis of the half-lifes of the respective mRNAs, have been partially or completely sequenced. To four have been assigned a definite function. cDNA10, which generates a long half-life mRNA, encodes the glucose-inducible form of the glycolytic enzyme, enolase. cDNAs 90, 39 and 13, each of which generates a short half-life mRNA, encode ribosomal proteins L3, L29 and YL6 respectively. cDNA46, which generates a long half-life mRNA, is related to a mouse gene of unknown function, MER5. In addition, there is circumstantial evidence that among the unidentified cDNAs that generate short half-life mRNAs are several that encode ribosomal proteins.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available