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Title: Asymmetric synthesis of β-lactams
Author: Brown, Alan Daniel
Awarding Body: University of Glasgow
Current Institution: University of Glasgow
Date of Award: 1990
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Several routes to optically enriched 2-azetidinones have been investigated. The most successful of these was that based on highly diastereoselective cycloaddition reactions between homochiral imines derived from (S)-methyl lactate and a range of achiral ketenes. The synthetic potential of the resulting azetidinones with respect to bicyclic beta-lactam formation has also been investigated.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available