Use this URL to cite or link to this record in EThOS: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.796183
Title: Platelet cytosolic free calcium and echocardiographic left ventricular mass in essential hypertension and primary hyperparathyroidism
Author: Dominiczak, Anna Felicja
Awarding Body: University of Glasgow
Current Institution: University of Glasgow
Date of Award: 1989
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Abstract:
Force development in cardiac and vascular muscle is directly related to the concentration of calcium ions in the cytosol. Sustained hypertension is predominantly maintained by an increase in total peripheral resistance and attention has therefore focused on the possibility that changes in intracellular calcium in myocytes of resistance vessels are important in the pathogenesis of essential hypertension in man. Apart from vascular tone, free calcium in cells also stimulates cell proliferation and growth and increased concentrations of calcium ions in cardiac and vascular smooth muscle could mediate the hypertrophy that characteristically occurs in response to an increase in wall tension.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (M.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.796183  DOI: Not available
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