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Title: Synthetic studies in the trichothecane field
Author: Malchenko, Swiatoslaw
Awarding Body: University of Glasgow
Current Institution: University of Glasgow
Date of Award: 1972
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Two synthetic routes towards 3,6-dimethyl-8-oxo-9-oxa-bicyclo[4,3,0]non-2-ene , a crucial intermediate in the synthesis of the sesquiterpenoid mould metabolite trichodermin, are discussed. The strategy and ultimate approach towards the most widely distributed sesquiterpenoid component of the tricho-thecanes, verrucarol, via 3-methyl-6-hydroxymethyl-8-oxo-9-oxabicyclo[4,3,0]non-2-ene,are fully described.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available