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Title: A mutational analysis of the DNA binding domain of the Herpes Simplex Virus immediate early protein Vmw175
Author: Allen, Kathryn Elizabeth
Awarding Body: University of Glasgow
Current Institution: University of Glasgow
Date of Award: 1993
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Upon infection, HSV-1 genes are transcribed by the host cell RNA polymerase II. The analysis of polypeptides synthesized during the course of HSV-1 lytic infection led to the identification of three co-ordinately regulated groups of genes, characterized by their specific temporal expression. The immediate-early or alpha genes are synthesized immediately following infection. Synthesis of immediate-early polypeptides is followed by the expression of early or beta genes, whilst the synthesis of late or gamma genes occurs subsequent to the onset of viral DNA synthesis.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available