Use this URL to cite or link to this record in EThOS: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.785399 |
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Title: | Investigation of cell-cell and cell-scaffold interactions through 2-D cell culture, 3-D tissue models and a simulated host system | ||||||
Author: | Gabbott, Christopher |
ISNI:
0000 0004 7970 9185
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Awarding Body: | Loughborough University | ||||||
Current Institution: | Loughborough University | ||||||
Date of Award: | 2018 | ||||||
Availability of Full Text: |
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Abstract: | |||||||
From the onset, the discipline of tissue engineering stated the promise of providing engineered tissues or organs for clinical applications. Nevertheless, this has remained an arduous task, due to the inadequate mechanistic understanding of the rudimentary cell-cell and cell-scaffold interactions that occur during tissue regeneration. Consequently, in this thesis, a simulated host environment was established, so that the costly and controversial in-vivo models could be superseded by in-vitro techniques, which can rapidly acquire insight of the aforementioned issues. However, due to the deficient knowledge in the field, the development of the simulated host system was hindered by several inaccurate conclusions which were fundamental prior to this thesis.
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Supervisor: | Not available | Sponsor: | EPSRC | ||||
Qualification Name: | Thesis (Ph.D.) | Qualification Level: | Doctoral | ||||
EThOS ID: | uk.bl.ethos.785399 | DOI: | Not available | ||||
Keywords: | Chemical Engineering not elsewhere classified | ||||||
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