Use this URL to cite or link to this record in EThOS: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.785361
Title: Some novel aspects of the synthesis of oxygen heterocycles
Author: McCarty, C. T.
Awarding Body: Loughborough University
Current Institution: Loughborough University
Date of Award: 1971
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Abstract:
The reactions of benzyne and tetrachlorobenzyne with αβ-unsaturated aldehydes which form 2-H-chromen derivatives have been investigated. The mechanism was established by [14C] and [2H] labelling experiments and proceeds initially through a benzoxeten intermediate. Subsequent opening of these intermediates followed by thermal cyclisation of an o-quinone methide gave the products. A degradation of 5,6,7,8-tetrachloro-2-H-flaven to a tetrachlorosalicylic acid derivative was carried out, to confirm the position of the [14C] radiolabel. Also described are a number of rearrangement reactions of 5,6,7,8-tetrachloro-4-H-flaven in which 2-benzoyl-dihydrobenzofuran, or 2-benzoyl-benzofuran derivatives were obtained if bromine was present in the reaction mixture.
Supervisor: Not available Sponsor: Science Research Council
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.785361  DOI: Not available
Keywords: Chemical Sciences not elsewhere classified
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