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Title: Twin screw granulation : understanding the mechanical properties of pharmaceutical excipients from powder to tablet
Author: Khorsheed, Bilal
ISNI:       0000 0004 7970 2303
Awarding Body: University of Sheffield
Current Institution: University of Sheffield
Date of Award: 2018
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The overall aim of this work is to understand the effect of the mechanical properties of the primary powder and the granulation process on granules and tablets properties, most importantly tablet tensile strength. The study investigated the mechanisms that dictate the change in tabletability before and after wet granulation using twin-screw granulation (TSG). Additionally, the research focused on improving the understanding of the relationship between the properties of the compressed materials and their tablet strength.
Supervisor: Salman, Agba ; Hounslow, Mike Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available