Volume I consists of three chapters. The first is a systematic literature review examining psychosocial factors associated with negative symptoms. The second is an empirical study of how mental health staff make sense of self-neglect in people with severe and enduring psychosis. The third is an executive summary, a public domain document providing an overview of the literature review and empirical paper. Volume II consists of five clinical practice reports (CPR's). The first CPR explores the case of a 23-year-old woman presenting with anxiety and anger. The case is formulated from a cognitive behavioural and psychodynamic perspective. The second CPR is a service evaluation exploring the views of mental health staff working in the community in relation to staff support when working with service users with a personality disorder. The third CPR is a case study of a 70-year-old woman presenting with GAD, describing and evaluating the assessment, formulation and intervention process. The fourth CPR is a single case experimental design evaluating the effectiveness of progressive muscle relaxation for a 20-year-old male with a mild learning disability. The fifth CPR is the abstract of an oral presentation of a case study of a 63-year-old female presenting with weight management difficulties.