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Title: Influence of fluid-structure interaction on human eye biomechanics under air puff non-contact tonometry
Author: Maklad, O.
ISNI:       0000 0004 7964 2566
Awarding Body: University of Liverpool
Current Institution: University of Liverpool
Date of Award: 2019
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Biomechanical properties of biological tissues are important health indicators and multiple clinical decisions and surgical planning can be made based on their dynamic response to loading. But until now, some of the mechanical and dynamic responses are not fully understood due to the non-linearity and viscoelastic behaviour of biological tissues. The relevant biological tissues of interest in the current study are the cornea and sclera of the human ocular globe. Cornea contributes with two-thirds of the optical focusing power of the eye beside intraocular lens and ocular fluids. The air puff tonometry test is a non-contact method with direct interaction to cornea in order to estimate the intraocular pressure which helps with early Glaucoma diagnosis. The gab in research of this area is considering the fluid-structure interaction effect between cornea, the air puff and the eye internal fluid. Numerical model of the air puff test was constructed in the context of a coupled model between computational fluid dynamics (CFD) and finite element analysis (FEA) using Arbitrary Lagrangian-Eulerian (ALE) deforming mesh. The time span of the jet is 30 ms and maximum Reynolds number (Re = 2.3×104), with jet orifice diameter 2.4 mm and impinging distance 11 mm. The present study was the first to take fluid-structure interaction between the air puff and cornea into account, in IOP and cornea material behaviour estimations.
Supervisor: Elsheikh, Ahmed ; Theofilis, Vassilis Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral