Use this URL to cite or link to this record in EThOS: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.776534
Title: Biochemical aspects of antibody production
Author: Moffat, George E.
Awarding Body: University of Glasgow
Current Institution: University of Glasgow
Date of Award: 1968
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Abstract:
The work presented in this thesis was directed towards developing a clearer understanding of some of the biochemical aspects of antibody production. The systems employed were rabbit-anti-bovine serum albumin (BSA) for studies on the specific activity of DNA polymerase, and rat-anti-sheep red blood cells (SHBC's) for polyribosome studies. Some rabbits were rendered tolerant to BSA by the intraperitoneal infection of this protein at birth. The establishment of tolerance was confirmed by antigen elimination tests in the mature animal. Comparative studies were made on the specific activity of DNA polymerase from the spleens and appendices of normal untreated rabbits, rabbits undergoing a primary or secondary response to BSA and rabbits previously rendered tolerant to BSA.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.776534  DOI: Not available
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