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Title: Muscle biopsy analysis of the body water and electrolyte content in health and disease
Author: Graham, John Alistair
Awarding Body: University of Glasgow
Current Institution: University of Glasgow
Date of Award: 1971
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The work presented in this thesis describes the measurement of body water and electrolyte contents by analysis of muscle biopsy-specimens. Biopsy-specimens were taken from skeletal muscle (usually vastus lateralis) under either local or general anaesthesia. Each biopsy-specimen is divided into three portions, which are weighed, dried and then weighed again. The total water content is thus obtained, and the total biopsy-specimen sodium, potassium and chloride content are then measured in an acid extract of the tissue. The total water and electrolyte contents are partitioned into extra- and intracellular phases using the chloride content of the biopsy-specimen (corrected for the intracellular content) as an indicator of the extracellular water.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (M.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available