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Title: Sequence studies on the high molecular weight RNA of HeLa cells
Author: Fraser, Nigel William
Awarding Body: University of Glasgow
Current Institution: University of Glasgow
Date of Award: 1975
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When growing cultures of mammalian cells are exposed to radioactive RNA precursors, two general types of very high molecular weight nuclear RNA can be recognised; ribosomal precursor RNA and a series of molecules, with molecular weight varying between 1 x 10⁶ and 20 x 10⁶, which have been collectively termed heterogeneous nuclear RNA (HnRNA). It is commonly believed that cytoplasmic messenger RNA is formed from nuclear HnRNA by post-transcriptional modification. The aim of this work was to examine the relationship between HnRNA and mRNA by studying short sequences present in them.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available