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Title: Humoral alloimmunity in cardiac allograft rejection
Author: Alsughayyir, Jawaher
ISNI:       0000 0004 7653 3858
Awarding Body: University of Cambridge
Current Institution: University of Cambridge
Date of Award: 2019
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Although the short-term outcomes of solid allograft survival have improved substantially over the last few decades, there has been no significant improvement in long-term survival of solid allografts. This thesis presents the initial characterisation of alloantibody mediated rejection in a murine heart transplant model, with particular focus on the impact of the different phases of the humoral alloimmune response (follicular or germinal centre) on graft rejection.
Supervisor: Pettigrew, Gavin Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
Keywords: Transplantation ; antibody-mediated rejection ; rejection ; organ transplantation