Use this URL to cite or link to this record in EThOS: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.761574
Title: Prevalence of depression and burden among informal caregivers of people with dementia and the effectiveness of mindfulness and acceptance based interventions at reducing these : two meta-analyses
Author: Collins, Rebecca Naomi
ISNI:       0000 0004 7652 7132
Awarding Body: University of East Anglia
Current Institution: University of East Anglia
Date of Award: 2018
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Abstract:
The primary aims of this thesis were to examine the prevalence of depression and burden among informal caregivers of people with dementia (PwD) and the effectiveness of mindfulness and acceptance based interventions (MABIs) at reducing these difficulties. The thesis consists of a meta-analysis on the prevalence of depression and burden among informal caregivers of PwD, a bridging chapter detailing the rationale behind the second meta-analysis set within the context of the first, a meta-analysis on the effectiveness of MABIs on depressive symptoms and burden among informal caregivers of PwD, an additional methodology chapter on the random-effects model, and an overall discussion and critical appraisal. The first meta-analysis identified 43 studies, examining a total of 16 911 participants. The adjusted pooled prevalence of depression was 31.2% (95% CI 27.7% to 35.0%) and burden was 49.3% (95% CI 37.2% to 61.5%). The second meta-analysis included 12 studies, providing data on 321 caregivers. MABIs proved largely and moderately effective at reducing depressive symptoms and burden among informal caregivers of PwD, respectively. There was, however, significant heterogeneity amongst almost all effect estimates reported. The first meta-analysis found the prevalence of depression differed according to the instrument used and the continent in which the study was conducted. The second meta-analysis was unable to explain the observed heterogeneity of effect sizes. Many of the included studies in the first and second meta-analysis were rated as having a ‘high risk’ of bias. The impact of heterogeneity and study quality is critically explored. The thesis indicates that there is a great need within this population for interventions that are effective at reducing burden and depressive symptoms, with MABIs appearing acceptable and beneficial. However, further higher quality research is needed to improve the robustness of the evidence bases and enable a meta-analysis to thoroughly examine and quantify moderator variables.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.761574  DOI: Not available
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