Volume I thesis consists of a systematic literature review, empirical research paper, and public dissemination document. The main finding of the systematic review was that sensation seeking is a significant predictor of alcohol use in adolescence, but does not always directly predict problem drinking and related problems. The empirical showed, among a sample of young males who have not attended university, impulsivity and negative consequences are directly related to alcohol use, but that it important to consider mediating and moderating variables that may impact the nature and direction of these relationships. The public dissemination document provides succinct and accessible summaries of both the systematic review and the empirical research paper. Volume II serves as a compilation of five Clinical Practice Reports (CPRs) conducted throughout the course of the Doctorate programme. This includes case studies, a single case evaluation design, a service evaluation and formulation of one case from two different models.