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Title: Healthcare quality improvement in emergency laparotomy surgery
Author: Huddart, Sam
ISNI:       0000 0004 7425 3617
Awarding Body: University of Surrey
Current Institution: University of Surrey
Date of Award: 2018
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Emergency laparotomies in the UK, and internationally, have a high risk of death, with accompanying evidence of suboptimal care. The emergency laparotomy pathway quality improvement care (ELPQuiC) bundle is a care bundle for patients undergoing emergency laparotomy, consisting of: initial assessment with early warning scores, early antibiotics, interval between decision and operation less than 6 hours, consultant-led intra-operative care, goal-directed fluid therapy and postoperative intensive care. The primary aim was to determine if implementation improved patient mortality after emergency laparotomy. Methods: The ELPQuiC bundle was implemented in four hospitals, using locally identified strategies to assess the impact on risk-adjusted mortality. Comparison of risk-adjusted 30-day mortality rates before and after care-bundle implementation was made using risk-adjusted cumulative sum (CUSUM) plots and a logistic regression model. Results: Risk-adjusted CUSUM plots showed an increase in the numbers of lives saved per 100 patients treated in all hospitals, from 6.47 in the baseline interval (299 patients included) to 12.44 after implementation (427 patients included) (P < 0.001). The overall risk-adjusted risk of death decreased from 15.6 to 9.6 per cent (risk ratio 0.614, 95 per cent confidence interval 0.451 to 0.836; P=0.002). There was an increase in the uptake of the ELPQuiC processes but no significant difference in the patient predicted risk of mortality profile as determined by the mean Portsmouth Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (P-POSSUM) risk (0.197 and 0.223 before and after implementation respectively; P=0.395). Conclusion: Use of the ELPQuiC bundle was associated with an increase in compliance to the majority of elements of the care bundle. Introduction of the ELPQuiC Bundle was associated with a significant reduction in the risk of death following emergency laparotomy.
Supervisor: Fry, Christopher Sponsor: Health Foundation
Qualification Name: Thesis (M.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available