Use this URL to cite or link to this record in EThOS: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.750980
Title: Antioxidant properties of ethoxyquin and some of its oxidation products
Author: Thorisson, Snorri
Awarding Body: University of St Andrews
Current Institution: University of St Andrews
Date of Award: 1988
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Abstract:
Ethoxyquin (1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline (I)), ethoxyquin nitroxide (II), 2,6-dihydro-2,2,4-trimetbyl-6-quinolone (III) and l,2-dihydro-6-hydroxy-2,2,4-trimethylquinoline (IV) were prepared and purified in order to study their antioxidant properties in fish meal and/or oil. I (also commercally available) and III were equally effective in fish meal, but III and IV were better in oil than I and II. In AIBN initiated methyl linoleate autoxidation, the order of efficiency in terms of the stoichiometric factor (n), using BHT as a standard, was IV > I > BHT > II. On the other hand, III gave very little inhibition in this system. In fish meal and oil, I was converted to III and to a 1,8'-dimer (V). The same products were formed in tert-butoxy oxidation of I. The nitroxide (II) was also formed from I but this was only seen by ESR in various organic solvents. It is likely to play some role in the antioxidant mechanism of I. The 1,8'-dimer was isolated and found to have no antioxidant properties in oil. Another reaction product of 1,2,4-dimethyl-6-ethoxyquinoline was also prepared. It was found to show prooxidant effects in fish oil.
Supervisor: Gunstone, F. D. Sponsor: International Association of Fish Meal Manufacturers
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.750980  DOI: Not available
Keywords: QP752.F35T7 ; Fatty acids
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