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Title: Synthesis of substituted azepanes and piperidines using organolithium chemistry
Author: Aeyad, Tahani
ISNI:       0000 0004 7226 8241
Awarding Body: University of Sheffield
Current Institution: University of Sheffield
Date of Award: 2018
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α-Amino-organolithium compounds represent an important class of intermediates due to their excellent nucleophilic reactivity and importance in synthetic organic chemistry. This thesis describes some novel aspects of the n-BuLi mediated lithiation‒substitution of N-Boc heterocycles, including N-Boc-2-substituted azepane, benzazepine and piperidine derivatives.
Supervisor: Coldham, Iain Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available