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Title: The discrete multi-physics method applied to biomechanics
Author: Ariane, Mostapha
ISNI:       0000 0004 7230 3561
Awarding Body: University of Birmingham
Current Institution: University of Birmingham
Date of Award: 2018
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In this thesis, a fully Lagrangian approach called the Discrete Multi-Physics is adopted and applied to biomechanics. The Discrete Multi-Physics combines the Smoothed Particle Hydrodynamics, the Mass and Spring Model and the Discrete Element Method in a common particle-based framework. In the Discrete Multi-Physics, high deformations and contact of solid structures (e.g. valve’s leaflets during closing phase or colloid contact) can be easily modelled. In biological valve simulations, for instance, we were able to account for repeated opening-closing cycles and to introduce an agglomeration algorithm to model clotting. Besides cardiovascular and venous flows, we also applied the Discrete Multi-Physics to respiratory tracts for modelling (i) cilia motion and drug diffusion in the periciliary layer (ciliated epithelium) and (ii) the release of active ingredients in powder inhalers for drug delivery in the lungs.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: QC Physics ; TP Chemical technology