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Title: Exercise in haemodialysis patients : impact on markers of inflammation
Author: Dungey, Maurice
ISNI:       0000 0004 7224 8187
Awarding Body: Loughborough University
Current Institution: Loughborough University
Date of Award: 2015
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End-stage renal disease patients have a greatly increased risk of cardiovascular disease partly attributed to the elevated levels of systemic inflammation observed in uraemia. One of the key mechanisms underlying inflammation appears to be the immune dysfunction that afflicts almost every aspect of the uraemic immune system. As a consequence patients experience immunosuppression and reduced responsiveness to antigen as well as a simultaneous over-activation leading to a pro-inflammatory environment. In addition, the haemodialysis (HD) treatment itself induces a proinflammatory response but may provide an otherwise opportune time to complete supervised exercise.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: Haemodialysis ; End-stage renal disease ; Exercise ; Inflammation ; Monocytes ; Cardiovascular disease ; Immune dysfunction ; Regulatory T cells