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Title: Alkylating derivatives of oestrogens as potentially target-selecting cytotoxic agents
Author: Lockey, Peter M.
Awarding Body: Loughborough University of Technology
Current Institution: Loughborough University
Date of Award: 1986
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The present work is a study of the structure–activity relationships and mode of action of oestrogens substituted with alkylating functions. These compounds are cytotoxic agents potentially selective for oestrogen-responsive tumours, since the oestrogen part of the molecule should lead to a concentration in tumour cells thereby imparting selectivity to the alkylating group.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available