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Title: Fluorescent probes for stimuli-responsive polymers : to fluoresce, or not to fluoresce?
Author: Mabire, Anne B.
ISNI:       0000 0004 7223 8157
Awarding Body: University of Warwick
Current Institution: University of Warwick
Date of Award: 2017
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This thesis explores the use of aminobromomaleimide and dithiomaleimide functionalities to probe their environment. These fluorescent functionalities were incorporated into responsive polymeric nanostructures allowing their behaviour to be read-out upon external stimuli. Chapter 1 gives a brief introduction on nanoparticles formation and the polymerisation techniques used throughout the thesis. The properties of bromo- and thio-maleimides and their use in protein and polymer chemistry were also introduced. Chapter 2 describes a morphology transition simultaneously with a fluorescence on-to-off switch as a result of the modification of the dithiomaleimide substituent. Chapter 3 presents the synthesis of a library of aminomaleimides and explores their fluorescent properties. In Chapter 4, the fluorescent properties of aminobromomaleimide were incorporated into CO2-responsive polymeric nanoparticles for a built-in read-out of the CO2-response. Chapter 5 explores the possibility of using the fluorescent properties of aminobromomaleimide to read-out the behaviour of glutathione-responsive particles.
Supervisor: Not available Sponsor: British Petroleum Company
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: QD Chemistry