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Title: Surgical aspects of water and salt metabolism
Author: Bingham, D. L. C.
Awarding Body: University of Edinburgh
Current Institution: University of Edinburgh
Date of Award: 1938
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I. Water and Salt metabolism has been discussed both in their theoretical and in their practical aspects. 2. A series of experiments was conducted on normal human subjects to prove or disprove certain conceptions of salt metabolism. 3. In general these conceptions were substantiated and, arising from this work the clinical applications are as follows: A. To diminish the mortality and morbidity from operations both water and electrolytes must be given in adequate amounts to restore or maintain normality. Two main types of problem therefore, may confront the surgeon. I. The case which comes under his care with depleted fluids and electrolytes and rules have been given for the restoration of both to normal. 2. The case which in hospital after operation loses electrolytes and fluids from vomiting, fistulae, etc. Such a case can be maintained in fluid balance by the application of the rules of water balance enunciated by W. G. Maddock and detailed in this paper. The electrolyte balance can also be maintained by the administration of a volume of 0.9% sodium chloride solution equal to the volume of the abnormal fluid losses (vomitus, drainage from fistulae etc.) without endangering the patient by overloading him with sodium chloride. B. The following table shows the degree of accuracy which results from the application of these rules, and I feel that, although much further work is needed fully to substantiate our claims, the clinical administration of sodium chloride has been placed on a sound basis.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available