| Use this URL to cite or link to this record in EThOS: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.734118 |
|
|||||||
| Title: | Stereochemical aspects in the aminoalkylation reactions of ketones | ||||||
| Author: | Fairhurst, Robin A. | ||||||
| Awarding Body: | Loughborough University of Technology | ||||||
| Current Institution: | Loughborough University | ||||||
| Date of Award: | 1991 | ||||||
| Availability of Full Text: |
|
||||||
| Abstract: | |||||||
|
A simple "one-pot" method has been developed for the amino-methylation of ketones possessing an α-hydrogen under aprotic conditions. The procedure utilises chlorotrimethylsilane in the sequential formation of the intermediate trimethylsilyl enol ether and methylene iminium species. The methylene iminium ion intermediate is generated either from a dialkylaminoalkoxymethane or a bis-(dialkylamino)methane.
|
|||||||
| Supervisor: | Not available | Sponsor: | SERC | ||||
| Qualification Name: | Thesis (Ph.D.) | Qualification Level: | Doctoral | ||||
| EThOS ID: | uk.bl.ethos.734118 | DOI: | Not available | ||||
| Share: | |||||||