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Title: A naturalistic study exploring the association between sleep and cognition in children with tic disorders
Author: Hibberd, Charlotte Jane
ISNI:       0000 0004 6498 1493
Awarding Body: King's College London
Current Institution: King's College London (University of London)
Date of Award: 2017
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Background: Sleep disturbances are common in children and young people with Tourette syndrome and chronic tic disorders (TS/CTD), although at present it is unclear whether any particular sleep problems could be considered typical of these conditions. It is also not known whether any identified patient characteristics, neurodevelopmental or psychiatric factors are associated with their presence in this group. Objectives: This review aimed to systematically explore types and frequency of sleep problems in children with TS/CTD. It aimed to examine the heterogeneity of previous studies in terms of sample characteristics and assessment methods and consider methodological quality of included studies. Methods: The Psycinfo, Ovid Medline, Embase and Web of Science databases were searched using a range of terms relating to tics, sleep and co-existing psychopathology. Studies were considered if they met a pre-determined set of criteria, including a sample of children with TS/CTD (n>5) for whom sleep disturbance was measured. 14 studies met criteria for inclusion in the review. Results: Overall, this review supported the high prevalence of sleep difficulties in children with TS/CTD, although rates varied widely from 17% to 80.4% (Interquartile Range (IQR) =21%-48%). A number of studies reported on other factors affecting sleep in this patient group including comorbidity, medication use and sample-related factors, such as age and gender. Studies varied in terms of methodology, sample and quality. Conclusions: The high rates of sleep problems in children with TS/CTD identified in this review, which was based on a small yet heterogeneous sample of papers, highlights the need for continued research in this area. The potential moderating factors and associated difficulties discussed here should be considered further to enhance understanding of the aetiology and management of sleep difficulties in this group.
Supervisor: Charman, Tony Sponsor: Not available
Qualification Name: Thesis (D.Clin.Psy.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available