In the thesis we investigate two problems on Partial Differential Equations (PDEs) in differential geometry and fluid mechanics. First, we prove the weak L ^p continuity of the Gauss-Codazzi-Ricci (GCR) equations, which serve as a compatibility condition for the isometric immersions of Riemannian and semi-Riemannian manifolds. Our arguments, based on the generalised compensated compactness theorems established via functional and micro-local analytic methods, are intrinsic and global. Second, we prove the vanishing viscosity limit of an incompressible fluid in three-dimensional smooth, curved domains, with the kinematic and Navier boundary conditions. It is shown that the strong solution of the Navier-Stokes equation in H ^r+1 (r > 5/2) converges to the strong solution of the Euler equation with the kinematic boundary condition in H ^r, as the viscosity tends to zero. For the proof, we derive energy estimates using the special geometric structure of the Navier boundary conditions; in particular, the second fundamental form of the fluid boundary and the vorticity thereon play a crucial role. In these projects we emphasise the linkages between the techniques in differential geometry and mathematical hydrodynamics.