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Title: Potentially inappropriate prescribing in older people : outcomes and assessments
Author: Cardwell, Karen
ISNI:       0000 0004 6423 923X
Awarding Body: Queen's University Belfast
Current Institution: Queen's University Belfast
Date of Award: 2017
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The overall aim of the research presented in this thesis was to report the prevalence of potentially inappropriate prescribing (PIP) in a specific cohort of people, identify the classes of medicines prescribed inappropriately and determine the association of PIP prevalence with a range of health-related outcomes. An additional aim was to explore the role of community pharmacists In screening for PIP using validated tools. The research described in this thesis was conducted as part of four studies. Using data from an on-going longitudinal study of ageing, entitled Life and living in advanced age: a cohort study in New Zealand (LiLACS NZ), Chapter 2 reports the prevalence of PIP and its association with health-related outcomes. In an effort to determine the most appropriate tool with which to measure anticholinergic medication burden in those aged £80 years, Chapter 3 comprised a systematic review of the literature surrounding the use of screening tools to quantify anticholinergic medication burden and its association with health-related outcomes. Following this, Chapter 4 utilised LiLACS NZ data to calculate participants' exposure to medications with anticholinergic and sedative properties, as measured by the Drug Burden index (DBI), and determine the association with a range of health-related outcomes. Given the developing role of the community pharmacist, the final chapter (Chapter 5) was an exploratory study of community pharmacists' views towards the utilisation of a screening tool to structure Medicines Use Reviews (MURs), as a means to improve the appropriateness of prescribing in older people. This study was qualitative in nature and utilised semi-structured interviews with community pharmacists to investigate their perceived role within the primary healthcare team, their views on PIP in older people, their opinions on provision of the current MUR service, as well as their opinions on the use of screening tools in the community pharmacy setting.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available