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Title: Genome structure and host interactions of Pieris granulosis viruses
Author: Smith, I. R. L.
Awarding Body: University of London
Current Institution: Imperial College London
Date of Award: 1987
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Previous studies have established that, while numerous Pieris granulosis viruses (ArGVs) are highly pathogenic for P. rapae only two are additionally infectious for P. brassicae, To seek relationships between genome structure and pathogenicity/ restriction endonuclease (RE) maps were constructed for seven isolates. A standardized system of RE fragment nomenclature was established/ and the zero point and orientation of physical maps were defined in relation to the location of the granulin gene. Estimates of genome size were in the range of 108 - 110 kilobase pairs. Genotypic variation among the seven isolates was detected in the form of lost or additional RE sites/ and of DNA insertions/ deletions. No definitive correlation between genome structure and virulence for P. brassicae could be identified from comparative mapping data alone.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available