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Title: Roles for the VEZF1 transcription factor in erythroid and housekeeping gene expression
Author: Al-Hosni, Aliya M. R.
ISNI:       0000 0004 6347 3139
Awarding Body: University of Glasgow
Current Institution: University of Glasgow
Date of Award: 2017
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VEZF1 is a DNA-binding transcription factor that is highly conserved in vertebrates. Human VEZF1 has recently been found to interact with transcriptionally active gene promoters and erythroid specific enhancers. It is unclear how the broadly expressed VEZF1 interacts with enhancers in a cell type-specific manner or what functions it plays at these elements. This work begins to address the cell-type specific roles of VEZF1 by creating loss of function models in a human erythroid cell line.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: Q Science (General) ; QH301 Biology ; QH345 Biochemistry ; QH426 Genetics