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Title: Functional genomic studies on the frog skin secretion of Phyllomedusa baltea and Phyllomedusa duellmani
Author: Wan, Yuantai
ISNI:       0000 0004 6060 1115
Awarding Body: Queen's University Belfast
Current Institution: Queen's University Belfast
Date of Award: 2016
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The skin of frogs has a significant role in their survival and their skin is not only permeable, allowing oxygen and water to be absorbed through it, but also acts as a first line of defence to fight infection by microorganisms. There are a number of glands in frog skin, which secrete different kinds of compounds. Primarily these chemicals keep the frogs moist. However, the frogs also benefit from many of these functional substances by being able to live in microbe-rich conditions as well in deterring predator attacks. The skin secretions from frogs contain various classes of biochemical, but peptides are predominant. It has been recognised that these peptides also possess considerable pharmacological and antimicrobial activities, some of which may potentially have significant medical applications. These data further illustrate that the skin secretions of Phyllomedusa (baltea/duellmani) frogs remain an important resource for novel peptide discovery, some of which may possess therapeutic properties.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available