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Title: Placental growth factor (PlGF) regulation and expression in endothelial cells
Author: Lal, Niraja Padmalata
ISNI:       0000 0004 6057 2430
Awarding Body: University of Birmingham
Current Institution: University of Birmingham
Date of Award: 2016
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The role of Placenta growth factor (PlGF) in physiological angiogenesis is quiescent, preclinical and human studies have established PlGF angiogenic activity to be regulated in pathologies. PlGF elicits its cellular functions via (vascular endothelial growth factor receptor) VEGFR-1 alone, and has gained more attention for its safety profile, especially when compared to the risks involved in VEGF-derived therapies. Loss and gain studies of PlGF function highlight the contribution of PlGF in disease aggravation or alleviation; however, factors regulating PlGF expression remains elusive.
Supervisor: Not available Sponsor: British Heart Foundation
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: QH426 Genetics ; RC Internal medicine