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Title: The impact of extreme physical exertion on salivary anti-microbial protein responses, circulatory endotoxin concentrations and cytokine profile : do probiotics have a role to play?
Author: Gill, Samantha
ISNI:       0000 0004 5989 6315
Awarding Body: Coventry University
Current Institution: Coventry University
Date of Award: 2016
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Extreme physical exertion is commonly associated with acute physiological changes in immune variables known to disturb host defences. Likely induced by the production of stress hormones (e.g., cortisol), partaking in ultra-endurance events with accompanying physiological stressors (e.g., environmental extremes, sleep deprivation and compromised hydration and (or) nutritional status) may amplify stress hormone responses and compromise immune status to a greater extent. To date, research investigating the impact of extreme physical exertion (e.g., ultra-marathon events) on physiological variables is extremely limited. More recently, the potential use of probiotics with known immunomodulatory effects may be considered an appropriate nutritional strategy to improve host defences and minimise and (or) prevent sub-clinical or clinically significant outcomes in active populations.
Supervisor: Thake, Doug ; Price, Mike Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: Exertion ; Running ; Endurance ; Probiotics