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Title: Modulation of the mitogen activated protein kinase pathway spatiotemporal signalling components : influence on pathway activation behaviour using an agent based model
Author: Shuaib, Aban
ISNI:       0000 0004 5990 3431
Awarding Body: University of Sheffield
Current Institution: University of Sheffield
Date of Award: 2016
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The subtleties of how the Mitogen Activated Protein Kinase works (MAPK) biochemical signalling pathway works, its emergent oscillatory behaviour and sensitivity is explained though an analysis of a computational agent based model that takes into account the distribution of the MAPK cascade components into multiple compartments.
Supervisor: Kiss-Toth, E. ; Holcombe, M. Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available