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Title: Investigation of the biological effects of mixtures of man-made and natural chemical food contaminants using in vitro bioassays
Author: Clarke, Rachel Sarah
ISNI:       0000 0004 5994 9923
Awarding Body: Queen's University Belfast
Current Institution: Queen's University Belfast
Date of Award: 2015
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Mycotoxins, heavy metals and pesticides are ubiquitous in the environment, contributing to multiple contamination of foodstuff. However, due to complications of determining their combined toxicity, legal limits of exposure are determined for single compounds, based on long standing toxicological techniques. Governmental regulatory bodies must begin to contemplate how to safeguard the population when such mixtures of contaminants are present in food. The aim of this thesis was to study the interactive and cytotoxic effects .of mixtures of chemical food contaminants when present at their corresponding regulatory limits, the capability of high content analysis (HCA)at determining these biological effects and to determine possible mechanistic approaches behind the adverse effects measured.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available