This portfolio thesis comprises of three parts. The first part is a systematic literature review, in which empirical literature relating to the use of Facebook groups in health conditions is explored. It aims to provide an understanding of how individuals with health conditions use Facebook groups. The review concludes with recommendations for future research. Part two is an empirical report of a study that used a qualitative approach of content analysis to explore the use of Facebook groups by those with a diagnosis of Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (M.E.). Participants completed an online survey and data was extracted from a single Facebook group. Results were considered in relation to the Shifting Perspectives Model of Chronic Illness (Paterson, 2001). Methodological limitations, potential clinical implications and areas of future research are also identified. Part three comprises the appendices and reflective statement. These include a statement reflecting on the research process and supplementary information pertaining to the literature review and empirical study.