Diabetes mellitus is the most common cause of end-stage renal disease requiring renal replacement therapy in the United Kingdom. However, many aspects of the prevalence, management and outcomes of diabetic patients with chronic kidney disease (CKD) remain unclear. This thesis consists of three studies using local (Northern Irish) data, national data (from the National Diabetes Audit) and international data (combined as part of a multi-centre collaborative meta-analysis). Its aims were to assess the survival of Northern Irish diabetic patients with CKD, examine the prevalence and associations of diabetes-related CKD in the UK National Diabetes Audit and to assess the association between glycosylated haemoglobin (HbA1c) and survival in diabetic haemodialysis patients.