Developing new routes towards precision and function in materials synthesis and properties / Dafni Moatsou This thesis explores three methods for the synthesis of materials with precise sequence and functions. Chapter 1 gives a brief introduction to the main concepts that underpin the methods used throughout the thesis. Chapter 2 examines the use of norbornenes for the synthesis of precision polymers via ring-opening metathesis polymerization by taking advantage of the different reactivity of different isomers of the monomers. Chapter 3 suggests the use of dioxepins for single monomer insertion in the ringopening metathesis polymerization of norbornenes. Chapter 4 describes the synthesis of a temperature-responsive protein-polymer bioconjugate and the study of its properties. Chapter 5 evaluates the synthetic parameters of L-proline-containing nanogels as a function of their ability to catalyze organic reactions. Chapter 6 discusses the attempt to modulate the cross-linking of nanogels by a photoreactive cross-linker based on thymine.