Certain dysfunctions of the alimentary tract - Achalasia of the Cardia, Pyloric Spasm, Megacolon, or Hirschprung's Disease - are considered to be part expressions of a generalised neurosis of psychogenic origin, in which heredity, various environmental factors, and infection, have a marked influence. The neurosis produces its effects by imbalance of the autonomic nervous system, and is benefited by psychotherapeutic treatment in conjunction with which drugs, physical measures, and surgical treatment have a limited place.