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Title: Molecular and functional characterisation of GABA-A receptors in the enteric nervous system of the mouse colon
Author: Seifi, Mohsen
ISNI:       0000 0004 5366 322X
Awarding Body: University of Portsmouth
Current Institution: University of Portsmouth
Date of Award: 2015
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The overall aims of my PhD research project were to identify which particular gamma-amino butyric acid A receptor (GABAAR) subunits are expressed by neurochemically defined cell-types of the enteric nervous system (ENS) of the mouse colon, and what effect the pharmacological activation of specific receptor subtypes had on colonic contractility, as well as assessing whether two key determinants of gastrointestinal (GI) plasticity, namely stress and ageing, altered such GABAAR expression and functional phenotypes in the colon.
Supervisor: Swinny, Jerome Dominic ; Brown, James Francis ; Mills, Jeremy James Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: Pharmacy