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Title: Simple morbid anatomical studies of the human stomach : an analysis of 78 cases
Author: Williams, A. Wynn
Awarding Body: University of Edinburgh
Current Institution: University of Edinburgh
Date of Award: 1949
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This work deals with the morbid - anatomical examination of 72 autopsy and 4 gastrectomy stomachs, all formalin- fixed. The specimens were fixed according to Magnus' rulings within a very short time of death. The stomachs are divided into 5 histological grades according to their health or disease. It is shown that the severity of "chronic gastritis" tends to increase with age, although it is pointed out that there are exceptions to this statement. Proof of the existence of physiological ageing of the stomach was not found. A correlation was attempted between the incidence and severity of chronic gastritis on the one hand and infection, uraemia and other factors on the other. Uraemia was constantly associated with chronic gastritis, often of severe degree. Severe chronic infections were often associated with severe chronic gastritis but sometimes such infections were associated with an almost normal gastric mucosa. Ulceration of the stomach was found in 15% of the adult cases. The average age of the patients was 67 and the ulcers were undiagnosed during life. Erosions were discovered in 30% of all stomachs exclusive of foetal stomachs. The pathogenesis of erosions and ulcers is briefly discussed. it is suggested that a vascular origin for erosions and ulcers is commoner than has frequently been supposed. This is supported by the common finding of haemorrhage in the mucosa and of all grades of erosion between 'pure' haemorrhagic erosions and typical miniature ulcers. Reference is made to particular cells of the inflamed mucosa and to 5 stomachs of particular interest.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (M.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available