The thesis describes the measurement of the local mass transfer coefficients on the surface of a small convex disc and on the surface of Petichek's stagnation point blood flow chamber. No correlation was found between the go mass transfer coefficients and the limited blood clot data available for those surfaces. The mass transfer measurements were made using the shrinking film holographic interferometry technique. The thesis details the interpretation of fringe patterns obtained on small, curved surfaces, and a method of determining the fringe order from a single hologram.