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Title: Identification of CACHD1 as a novel [alpha]2[delta]-like auxiliary subunit of Cav3 voltage-gated calcium channels
Author: Soubrane, Camille Hélène
ISNI:       0000 0004 5351 5892
Awarding Body: University of Reading
Current Institution: University of Reading
Date of Award: 2014
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The putative CACHD1 gene was identified following a systematic search for ligand-binding proteins as novel drug targets. The CACHD1 gene encodes CACHD1 and has a predicted protein structure similar to that of the [alpha]2[delta] family of voltage-gated Ca2+ channel (VGCC) auxiliary subunits, which modulates the biophysical properties and plasma membrane expression of VGCCs. On this basis, the hypothesis that CACHD1 represents a novel [alpha]2[delta]-like VGCC auxiliary subunit was tested.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available