| Use this URL to cite or link to this record in EThOS: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.658003 |
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| Title: | Identification of CACHD1 as a novel [alpha]2[delta]-like auxiliary subunit of Cav3 voltage-gated calcium channels | ||||
| Author: | Soubrane, Camille Hélène |
ISNI:
0000 0004 5351 5892
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| Awarding Body: | University of Reading | ||||
| Current Institution: | University of Reading | ||||
| Date of Award: | 2014 | ||||
| Availability of Full Text: |
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| Abstract: | |||||
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The putative CACHD1 gene was identified following a systematic search for ligand-binding
proteins as novel drug targets. The CACHD1 gene encodes CACHD1 and has a
predicted protein structure similar to that of the [alpha]2[delta] family of voltage-gated Ca2+
channel (VGCC) auxiliary subunits, which modulates the biophysical properties and
plasma membrane expression of VGCCs. On this basis, the hypothesis that CACHD1
represents a novel [alpha]2[delta]-like VGCC auxiliary subunit was tested.
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| Supervisor: | Not available | Sponsor: | Not available | ||
| Qualification Name: | Thesis (Ph.D.) | Qualification Level: | Doctoral | ||
| EThOS ID: | uk.bl.ethos.658003 | DOI: | Not available | ||
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