In this thesis a new signal processing technique is presented. This technique exploits the use of pulses as the signalling mechanism. This Palmo signalling method applied to signal processing is novel, combining the advantages of both digital and analogue techniques. Pulsed signals are robust, inherently low-power, easily regenerated, and easily distributed across and between chips. The Palmo cells used to perform analogue operations on the pulsed signals are compact, fast, simple and programmable. To demonstrate the inherent suitability of the technique to programmable analogue implementations, two chips were fabricated and tested on boards containing a standard FPGA for doing the routing. Results from elementary filter implementations and A/D converters are presented to prove the validity of the approach. Finally a current-mode log-domain BiCMOS Palmo circuit is analysed, which enables much higher sample frequencies than the voltage domain Palmo counterparts.