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Title: Observations on the action of digitalis in man
Author: Fraser, F. R.
Awarding Body: University of Edinburgh
Current Institution: University of Edinburgh
Date of Award: 1922
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In recent years evidence has been produced that makes clearer certain points that have been observed by clinicians during the administration of digitalis for therapeutic purposes, that helps to indicate with more certainty the effect that can be expected in a particular case, and that enables the drug to be administered with greater efficiency. The author of this thesis has worked in collaboration with others in producing some of this evidence, and some of the results have already been published as follows:- 1. Certain Effects of Digitalis on the Heart. Cohn and Fraser. International Congress of Medicine. London,1913. 2. The Influence of Digitalis on the T wave of the Human Electrocardiogram. Cohn, Fraser and Jamieson. Journal of Experimental Medicine. Vol. XXI, June, 1915. The Author of this thesis had clinical charge of the cases employed in the investigations. The electrocardiographic records were made and analysed by him under the direction of Dr. A.E. Cohn, but for the analysis and discussion here presented the author is entirely responsible. The preparation of this thesis was commenced in 1914 but was interrupted by the war. In a field of this nature, where so many observers have been engaged, it is necessary to indicate the work of others, whether previous or contemporary, to such an extent that the sequence 1. of thought may he maintained, hut it is impossible to refer to much work of importance that has helped to build up the present knowledge of the actions of the digitalis bodies. The observations will be recorded in so far as they apply to our knowledge of the action of digitalis in human beings on :- (I) the normal pace-maker of the heart; (II) the auriculo-ventricular conducting mechanism; (III) the ventricular muscle.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (M.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available