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Title: Factors affecting the biovailability of dietary anthocyanins
Author: Cahyana, Yana
ISNI:       0000 0004 5353 9835
Awarding Body: University of Reading
Current Institution: University of Reading
Date of Award: 2014
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Beneficial health effects of anthocyanin-rich fruits and vegetables have been well documented. Subsequently extensive research on anthocyanins has been carried out to better understand the behaviour of anthocyanins. Bioavailability is one aspect which has been frequently investigated but the studies have not studied factors affecting anthocyanin bioavailability. Knowledge of the mechanism of anthocyanin absorption is also lacking. A bioavailability study was conducted with human volunteers whose urine was analysed following consumption of strawberry and red grape juice. Since anthocyanins are absorbed and present in biological fluids, their interactions with human serum albumin (HSA) were further examined. The study was then completed with an in-vitro test using Caco-2 cells to assess the uptake of anthocyanins by intestinal cells, and factors affecting uptake and the absorption mechanism through the apical cellular membrane.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available